To define rates of priapism diagnosis and inpatient admission among males with SCD.
We retrospectively reviewed the Pediatric Health Information System database for males aged <21 years treated 2004-2012.
We identified patients with SCD and priapism based on ICD-9-CM diagnosis codes. Logistic regression and generalized estimating equation models were used to control for confounding and to adjust for within-hospital clustering of similar patients.
We identified 17,186 males who were admitted 137,710 times during the study period. Of these, 362 (2. 1%) were diagnosed with priapism on 748 admissions. There was a significant decrease in the number of priapism admissions among patients with SCD over time (0. 81% in 2004 to 0. 44% in 2012, p<0. 001). The number of patients diagnosed with SCD-related priapism varied over time without a statistically significant trend (2. 3% in 2004, 2. 69% in 2008, 1. 01% in 2012, p=0. 34). Rates of priapism admissions (0-4. 4%) varied widely between hospitals. Older patient age was associated with an increased likelihood of a priapism admission in the multivariate logistic regression model after adjusting for treatment year, hospital region, and for hospital-level clustering of similar patients.
From 2004-2012, the number of admissions for SCD-related priapism declined while the number of individual patients diagnosed with SCD-related priapism did not. Rates of priapism-related admissions in males with SCD vary widely among PHIS hospitals.
Urology. 2015 Dec 07 [Epub ahead of print]
Hsin-Hsiao Scott Wang, Katherine W Herbst, Jennifer A Rothman, Nirmish R Shah, John S Wiener, Jonathan C Routh
Department of Surgery, Duke University Medical Center, Durham, NC. , Department of Urology, Connecticut Children's Medical Center, Hartford, CT. , Department of Pediatrics, Duke University Medical Center, Durham, NC. , Department of Pediatrics, Duke University Medical Center, Durham, NC; Department of Medicine, Duke University Medical Center, Durham, NC. , Department of Surgery, Duke University Medical Center, Durham, NC; Department of Pediatrics, Duke University Medical Center, Durham, NC. , Department of Surgery, Duke University Medical Center, Durham, NC; Department of Pediatrics, Duke University Medical Center, Durham, NC.