Impact of a multidisciplinary evaluation in pediatric patients with nocturnal monosymptomatic enuresis

BACKGROUND - Enuresis (NE) is a clinical condition of multifactorial etiology that leads to difficulties in child/adolescent social interaction.

METHODS - This was a prospective study on the impact of multidisciplinary assessment of 6- to 17-year-old patients with monosymptomatic nocturnal enuresis (MNE), including a structured history, clinical/neurological examination, bladder and bowel diaries, sleep diary and questionnaires, psychological evaluation [Child Behavior Checklist (CBCL) and PedsQL 4.

0 questionnaires], urinary sonography, blood and urine laboratory tests, polysonography (PSG), and balance evaluation.

RESULTS - A total of 140 enuretic participants were evaluated, of whom 27 were diagnosed with NE complicated by urinary disorder, four with hypercalciuria, three with nephropathy and one with attention-deficit hyperactivity disorder. Among the 87 participants who underwent PSG, six were diagnosed with severe apnea. Of the 82 MNE patients who underwent full assessment, 62 were male (75.6 %), and the mean age was 9.5 (±2.6) years. A family history of NE was diagnosed in 91.1 % of first- and second-degree relatives, constipation in 89.3 % and mild/moderate apnea in 40.7 %. Balance control alteration was identified by physical therapy evaluation of MNE patients. Participants' quality of life evaluation scores were significantly lower than those of their parents.

CONCLUSIONS - Enuresis is a multifactorial disorder that requires a structured diagnostic approach.

Pediatric nephrology (Berlin, Germany). 2016 Feb 25 [Epub ahead of print]

Simone Nascimento Fagundes, Leticia Azevedo Soster, Adrienne Surri Lebl, Rita Pavione Rodrigues Pereira, Clarice Tanaka, Rodrigo Fernando Pereira, Edwiges Ferreira de Mattos Silvares, Vera H Koch

Pediatric Nephrology Unit, Instituto da Criança Hospital das Clinicas University of São Paulo Medical School, Rua Lydia Ferrari Magnoli, 300 ap 21 Jardim Avelino, São Paulo, 03227085, São Paulo, Brazil.   Pediatric Sleep Laboratory-Instituto da Criança Hospital das Clinicas, University of São Paulo Medical School, São Paulo, São Paulo, Brazil., Pediatric Nephrology Unit, Instituto da Criança Hospital das Clinicas, University of São Paulo Medical School, São Paulo, São Paulo, Brazil., Department of Physical Therapy, Speech Therapy and Occupational Therapy, University of São Paulo Medical School, São Paulo, São Paulo, Brazil., Department of Physical Therapy, Speech Therapy and Occupational Therapy, University of São Paulo Medical School, São Paulo, São Paulo, Brazil., Urology Department, ABC Medical School, São Paulo, São Paulo, Brazil., Clinical Psychology Department, University of São Paulo, São Paulo, São Paulo, Brazil., Pediatric Nephrology Unit, Instituto da Criança Hospital das Clinicas, University of São Paulo Medical School, São Paulo, São Paulo, Brazil.