Wilms tumor is the most common renal tumor in children, and the 5-year survival rate is approximately 85%. The majority of relapses occur in the lung, tumor bed, and liver within 2 years of diagnosis.
In this study, we describe an unusual late tumor recurrence that occurred 9.5 years after the primary diagnosis. The patient presented with a slow growing cervical lymphadenopathy. The recurrent tumor showed the same histologic features as the original tumor. The patient was treated with surgery and radiotherapy without chemotherapy. The patient remained disease free 15 months after treatment. The possible effect of treatment and other mechanisms of this late relapse are discussed.
Journal of pediatric hematology/oncology. 2016 Feb 22 [Epub ahead of print]
Hélène Sudour-Bonnange, Cyril Lervat, Florence Renaud, Hélène Gauthier, Nathalie Rocourt
*Pediatric Oncology Unit †Nuclear Medicine Department §Radiology Department, Anti-Cancer Center Oscar Lambret ‡Department of Pathology, University Hospital of Lille, Lille, France.