To identify the circadian sensitive component of nocturia comparing nocturia in patients who voluntarily choose a disrupted circadian rhythm, i.e. shift workers, with those who maintain normal day-night cycles.
A total of 1,741 untreated patients, 1,376 non-shift workers and 365 shift workers, between 2011 and 2013 were compared for nocturia indices based on frequency volume charts (FVC). General linear model of 8 hour interval urine production and frequency were compared between FVCs of non-shift workers, night shift FVCs and day shift FVCs of shift workers.
Nocturia frequency was increased in the night shift of shift workers (2. 38±1. 44) compared to non-shift workers (2. 18±1. 04) (p
Patients in alternating shifts showed increased nocturia, especially during their night shift. These changes tended to be more associated with decreased nocturnal bladder capacity than increased nocturnal polyuria.
Urology. 2015 Sep 08 [Epub ahead of print]
Jin Wook Kim
Chung Ang University, College of Medicine, Department of Urology.