Nocturia is common among patients with type 2 diabetes mellitus, but limited evidence regarding the association between body mass index (BMI) and nocturia exists among such patients. The aim of the present study, therefore, was to evaluate the association between BMI and nocturia among Japanese patients with type 2 diabetes mellitus.
Study participants were 809 Japanese patients with type 2 diabetes mellitus. Study participants were considered to have nocturia if they answered "two or more" to the question: "How many times do you typically wake up to urinate from sleeping at night until waking in the morning?" We used the following two outcomes: (i) moderate nocturia was defined as ≥2 voids per night; and (ii) severe nocturia was defined as ≥3 voids per night. Participants were categorized into four groups according to their BMI: (i) BMI <18.5; (ii) 18.5 ≤ BMI < 25; (iii) 25 ≤ BMI < 30; and (iv) BMI ≥30. Multiple logistical regression analysis for nocturia in relation to BMI was used, with the category of 18.5 ≤ BMI < 25 as the reference.
Obesity (BMI ≥30) was independently positively associated with severe nocturia among elderly patients (age ≥65 years) with type 2 diabetes mellitus, but not among young and middle-aged patients: the adjusted OR was 2.96 (95% CI 1.10-7.83). BMI was not associated with moderate nocturia in all patients.
In Japanese elderly patients with type 2 diabetes mellitus, obesity was independently positively associated with severe nocturia. Geriatr Gerontol Int 2017; ••: ••-••.
Geriatrics & gerontology international. 2017 Jun 28 [Epub ahead of print]
Shinya Furukawa, Takenori Sakai, Tetsuji Niiya, Hiroaki Miyaoka, Teruki Miyake, Shin Yamamoto, Koutatsu Maruyama, Keiko Tanaka, Teruhisa Ueda, Hidenori Senba, Masamoto Torisu, Hisaka Minami, Takeshi Tanigawa, Bunzo Matsuura, Yoichi Hiasa, Yoshihiro Miyake
Department of Epidemiology and Preventive Medicine, Ehime University Graduate School of Medicine, Ehime, Japan., Department of Internal Medicine, Yawatahama General City Hospital, Ehime, Japan., Department of Internal Medicine, Matsuyama Shimin Hospital, Ehime, Japan., Department of Internal Medicine, Saiseikai Matsuyama Hospital, Ehime, Japan., Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Ehime, Japan., Department of Lifestyle-related Medicine and Endocrinology, Ehime University Graduate School of Medicine, Ehime, Japan., Department of Public Health, Juntendo University School of Medicine, Tokyo, Japan., Department of Internal Medicine, Ehime Central Hospital, Ehime, Japan., Department of Internal Medicine, Saiseikai Saijo Hospital, Ehime, Japan., Department of Internal Medicine, Ehime Niihama Hospital, Ehime, Japan.