Shifting the treatment paradigm in idiopathic overactive bladder.

Overactive Bladder (OAB) is the term used to describe the symptom complex of urinary urgency, usually accompanied by frequency and nocturia, with or without urgency urinary incontinence (UUI; or OAB Wet and Dry, respectively), in the absence of urinary tract infection (UTI) or other obvious pathology. Approximately 50% of patients with OAB are found to have urodynamic detrusor overactivity (UDO) during urodynamic investigations; when looking at those with more severe symptoms and who are incontinent (OAB wet) the figures for UDO are 90% and approximately 60% for men and women, respectively. Uncontrolled UDO may lead to medical sequelae, such as upper urinary tract complications and renal failure.

International journal of clinical practice. 2020 Nov 21 [Epub ahead of print]

Arun Sahai, Mo Belal, Rizwan Hamid, Phillip Toozs-Hobson, Paraskeve Granitsiotis, Dudley Robinson

Consultant Urologist, Guy's and St Thomas' Hospital., Consultant Urological Surgeon, Queen Elizabeth Hospital, Birmingham., Consultant Urologist, University College Hospital, London., Consultant Urogynaecologist, Birmingham Women's and Children's Hospital Nhs Foundation Trust, Birmingham., Consultant Urologist, Western General Hospital, Edinburgh., Consultant Urogynaecologist, Kings College Hospital, London.