Microbiologist in the Clinic: Postmenopausal Woman with Chronic OAB and Positive Urine Culture.

In this second episode of the Microbiologist in the Clinic series, clinicians and laboratory scientists share their perspectives about a 75-year-old woman who was diagnosed with asymptomatic bacteriuria based on positive urine cultures. The patient and her GP are concerned about this laboratory finding as the patient will become immunosuppressed with planned chemotherapy. The patient has had an overactive bladder (OAB) for approximately 20 years, with good control of her urinary urgency and frequency (no incontinence) with a stable dose of OAB medication. The challenges of this clinical presentation are discussed, with evidence for evaluation and treatment.

International urogynecology journal. 2024 May 27 [Epub ahead of print]

Linda Brubaker, Harry Horsley, Rajvinder Khasriya, Alan J Wolfe

Division of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics, Gynecology and Reproductive Sciences, University of California San Diego, La Jolla, CA, USA. ., Department of Renal Medicine, Division of Medicine, UCL, London, UK., Eastman Dental Institute, Department of Microbial Disease, UCL, London, UK., Department of Microbiology and Immunology, Loyola University, Chicago, IL, USA.