The purpose of this guideline is to provide evidence-based guidance to clinicians of all specialties on the evaluation, management, and treatment of idiopathic overactive bladder (OAB). The guideline informs the reader on valid diagnostic processes and provides an approach to selecting treatment options for patients with OAB through the shared decision-making process, which will maximize symptom control and quality of life, while minimizing adverse events and burden of disease.
An electronic search employing OVID was used to systematically search the MEDLINE and EMBASE databases, as well as the Cochrane Library, for systematic reviews and primary studies evaluating diagnosis and treatment of OAB from January 2013 to November 2023. Criteria for inclusion and exclusion of studies were based on the Key Questions and the populations, interventions, comparators, outcomes, timing, types of studies and settings (PICOTS) of interest. Following the study selection process, 159 studies were included and were used to inform evidence-based recommendation statements.
This guideline produced 33 statements that cover the evaluation and diagnosis of the patient with symptoms suggestive of OAB; the treatment options for patients with OAB, including Noninvasive therapies, pharmacotherapy, minimally invasive therapies, invasive therapies, and indwelling catheters; and the management of patients with BPH and OAB.
Once the diagnosis of OAB is made, the clinician and the patient with OAB have a variety of treatment options to choose from and should, through shared decision-making, formulate a personalized treatment approach taking into account evidence-based recommendations as well as patient values and preferences.
Neurourology and urodynamics. 2024 Jul 15 [Epub ahead of print]
Anne P Cameron, Doreen E Chung, Elodi J Dielubanza, Ekene Enemchukwu, David A Ginsberg, Brian T Helfand, Brian J Linder, W Stuart Reynolds, Eric S Rovner, Lesley Souter, Anne M Suskind, Elizabeth Takacs, Blayne Welk, Ariana L Smith
Department of Urology, University of Michigan, Ann Arbor, Michigan., Department of Urology, Columbia University, New York, New York., Department of Urology, University of Southern California, Palo Alto, California., Department of Urology, Stanford University School of Medicine, Palo Alto, California., Department of Urology, University of Southern California, Los Angeles, California., Northshore Health System, Glenview, Illinois., Department of Urology, Mayo Clinic, Rochester, Minnesota., Department of Urology, Vanderbilt University Medical Center, Nashville, Tennessee., Department of Urology, Medical University of South Carolina, Charleston, South Carolina., Nomadic EBM Methodology, Smithville, Ontario, Canada., Department of Urology, University of California, San Francisco, San Francisco, California., Mason City Clinic, Mason City, Iowa., Department of Surgery and Epidemiology & Biostatistics, Western University, London, Ontario, Canada., Division of Urology, University of Pennsylvania, Philadelphia, Pennsylvania.