OBJECTIVE: Metabolic syndrome (MS) risk factors are potentially implicated in the development of lower urinary tract symptoms (LUTS).
The goals of this study were to analyze the prevalence of the LUTS in patients presenting with MS and to evaluate the correlation between the MS components and LUTS.
METHODS: A prospective study was conducted on a group of 34 patients with MS according to the criteria of the NCEP ATP III. Urinary symptom profile (USP) questionnaire was used to evaluate LUTS. The physical examination included: weight, waist circumference, body mass index (BMI) and blood pressure looking for orthostatic hypotension. The following laboratory data were obtained: fasting blood sugar, postprandial glycemia, glycosylated hemoglobin (HbA1c), HDL-cholesterol, LDL-cholesterol, triglycerides and total cholesterol.
RESULTS: The mean age was 56.2 years (±9.2). Twenty of the patients (58.8%) were females. All patients underwent diabetic and hypertension therapy. The mean BMI was 30.2±4.8 and waist circumference was 107.8±9.3cm. USP total score was 8.3±6. Besides, 29 (85.2%) patients had overactive bladder symptom, and 13 (38.2%) patients presented with urinary stress incontinence. The overactive bladder USP score was significantly correlated with age, waist circumference, BMI and postprandial glycemia. The other parameters of MS were not correlated with urinary symptoms.
CONCLUSION: The most frequent urinary symptom in the MS was overactive bladder symptoms and urinary incontinence. The components of MS that influenced the USP score were abdominal obesity and hyperglycemia. The hypothesis of a link between MS and overactive bladder in diabetic patients with MS is plausible.
Written by:
Boudokhane S, Marmouche H, Klii R, Jellad A, Mahjoub S, Ben Salah Frih Z. Are you the author?
Service de rééducation fonctionnelle, faculté de médecine de Monastir, centre hospitalo-universitaire Fattouma Bourguiba de Monastir, avenue 1-Juin, 5000 Monastir, Tunisie.
Reference: Prog Urol. 2013 Apr;23(4):256-61.
doi: doi: 10.1016/j.purol.2012.10.009
PubMed Abstract
PMID: 23544983
Article in French.
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