Overactive bladder (OAB), a clinically defined symptom complex comprising urinary urgency, usually accompanied by urinary frequency and nocturia, with or without urgency incontinence, is common and has a markedly negative impact on the sufferer's quality of life.
Following conservative and lifestyle management, the current pharmacological mainstay of treatment is antimuscarinic therapy. This review explores the role of fesoterodine, a relatively recently introduced antimuscarinic agent, in the treatment of patients who may have had a suboptimal response to initial therapy, who have switched treatment from tolterodine, or may be at risk of receiving poor treatment because of either multimorbidity or complex polypharmacy.
Written by:
Morris V, Wagg A. Are you the author?
Geriatric Medicine, Taunton Hospital Somerset, UK; Division of Geriatric Medicine, University of Alberta, Edmonton, Alberta, Canada.
Reference: Drug Des Devel Ther. 2014 Jan 9;8:113-119.
doi: 10.2147/DDDT.S40032
PubMed Abstract
PMID: 24470751
UroToday.com Overactive Bladder (OAB) Section