Objective: The aim of this study was to explore the relationship between voided volume (VV) and urge to void among patients with lower urinary tract symptoms.
Material and Methods: Consecutive adult patients (aged 23-90 years) were enrolled, and completed a 24 h bladder diary and the Urgency Perception Scale (UPS). Patients were categorized as urgency or non-urgency based on the Overactive Bladder Symptom Score. The relationship between UPS and VV (based on the bladder diary) was analyzed by Spearman's rho and proportional odds model.
Results: In total, 1265 micturitions were evaluated in 117 individuals (41 men, 76 women; 56 individuals in the urgency and 61 in the non-urgency group). The mean (± SD) VV and UPS were 192 ± 127 ml and 2.4 ± 1.2 ml in the urgency group and 173 ± 124 ml and 1.7 ± 1.1 ml in the non-urgency group, respectively. Spearman's rho (between UPS and VV) was 0.21 (95% confidence interval (CI) 0.13-029, p < 0.001) for the urgency group, 0.32 (95% CI 0.25-0.39, p < 0.001) for the non-urgency group, and 0.28 (95% CI 0.23-0.33, p < 0.001) for the total cohort. Urgency patients had higher UPS (odds ratio (OR) 3.1, 95% CI 2.5-3.8). Overall, each additional 50 ml VV increased the odds of having a higher UPS with OR 1.2 (95% CI 1.2-1.3). The relationship between VV and UPS score was similar in both groups (p = 0.548 for interaction).
Conclusion: Although urgency patients void with a higher UPS score, among both urgency and non-urgency patients there is only a weak correlation between VV and the urge to void. This suggests that there are factors other than VV that cause the urge to void.
Written by:
Blaivas JG, Tsui JF, Amirian M, Ranasinghe B, Weiss JP, Haukka J, Tikkinen KA. Are you the author?
Department of Urology, SUNY Downstate Medical Center, Brooklyn, New York, USA.
Reference: Scand J Urol. 2014 Jul 16:1-5.
doi: 10.3109/21681805.2014.932842
PubMed Abstract
PMID: 25029069
UroToday.com Overactive Bladder (OAB) Section
