Perspective study of urodynamic factors with pre- and post-operation overactive bladder symptoms for anterior vaginal prolapse - Abstract

OBJECTIVE: To identify pre-operative demographic and urodynamic (UD) parameters related to overactive bladder (OAB) symptoms of pre-operation and persistence of after pelvic organ prolapse (POP) repair.

METHODS: From Jan 1, 2010 to Oct 31, 2012, this perspective study examined demographic and UD data of 175 patients undergoing POP surgery. Pre- and post- operative urinary distress inventory 6 (UDI- 6) scores for frequency and urge urinary incontinence (UUI) were analyzed, and correlations between scores and pre-operative UD data were also analyzed.

RESULTS: (1)Surgery resulted in a improvement of frequency (71.0% , 71/100) and UUI (69.2% , 63/91) at 12-24 months follow-up. (2)Pre-operative UD parameters: first desire of bladder < 100 ml, 6.3% (11/175); detrusor overactivity, 14.9% (26/175); post-void residual ≥50 ml, 11.4% (20/175); maximal flow rate (Qmax), (16±7) ml/s. (3)Comparison of pre- operative UD datas between patients with OAB symptoms and without, with OAB symptoms group had more patients of type III stress urinary incontinence (5% (5/91) versus 0 (0/84), P = 0.022). (4)Qmax was higher in improvement in UUI group than that in persistent UUI after POP repair ((17±7) ml/s versus (13±5) ml/s, P < 0.01).

CONCLUSIONS: POP repair significantly reduces OAB symptoms; however, there had not exact predictor for symptoms of persistent frequency, UUI after POP repair. Persistent UUI symptom may be related to Qmax of pre-operative UD.

Written by:
Yang X, Tan C, An F, Sun X, Wang J.   Are you the author?
Department of Obstetrics and Gynecology, Peking University People's Hospital, Beijing 100044, China.  

Reference: Zhonghua Fu Chan Ke Za Zhi. 2014 Nov;49(11):829-33.


PubMed Abstract
PMID: 25603907

Article in Chinese.

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