BACKGROUND: Previous studies have reported high rates of depression and anxiety in HTLV-1 infected individuals with the neurological disease and in the asymptomatic phase.
No study has investigated the rates in individuals that already show bladder symptoms without severe neurological changes; that is, during the oligosymptomatic phase. The present study investigated patients in this intermediate form on the spectrum of the infection.
METHODOLOGY/PRINCIPAL FINDINGS: Participants answered a sociodemographic questionnaire, the Mini International Neuropsychiatric Interview Brazilian Version 5.0.0 (MINI PLUS) and the Hospital Anxiety and Depression Scale (HADS). Data analysis was performed in STATA statistical software (version 12.0). Depressive disorder was the most frequent comorbidity. Current depressive disorder was higher in the group of overactive bladder subjects (11.9%), and lifelong depression was more frequent in the HAM/TSP group (35%). The three groups had similar frequencies of anxiety disorders. Increased frequency and severity of anxiety and depression symptoms were observed in the overactive bladder group.
CONCLUSION/SIGNIFICANCE: The results suggest that individuals with overactive bladders need a more thorough assessment from the mental health perspective. These patients remain an understudied group regarding psychiatric comorbidities.
Written by:
Orge GO, Dellavechia TR, Carneiro-Neto JA, Araújo-de-Freitas L, Daltro CH, Santos CT, Quarantini LC. Are you the author?
Programa de Pós-graduação em Medicina e Saúde, Universidade Federal da Bahia, Salvador, BA, Brasil; Programa de Pós-Graduação em Ciências da Saúde, Universidade Federal da Bahia, Salvador, BA, Brasil; Escola de Nutrição, Universidade Federal da Bahia, Salvador, BA, Brasil; Departamento de Ciências Exatas, Universidade Estadual de Feira de Santana, Feira de Santana, BA, Brasil; Instituto de Saúde Coletiva, Universidade Federal da Bahia, Salvador, BA, Brasil; Departamento de Neurociências, Hospital Universitário Professor Edgard Santos, Universidade Federal da Bahia, Salvador, BA, Brasil.
Reference: PLoS One. 2015 May 27;10(5):e0128103.
doi: 10.1371/journal.pone.0128103
PubMed Abstract
PMID: 26018525