The objective of this study was to assess the resource use of treating overactive bladder (OAB) patients in real-world clinical practice and to evaluate whether there is external validity in the treatment of OAB in clinical practice.
The study included 55 patients suffering from OAB and treated with BOTOX(®) at two Swedish clinics. The study was conducted as an anonymized retrospective chart review study.
The estimated yearly direct cost of BOTOX treatment was €902. The mean age of patients in the study was 60 years, and 85% were women. The severity of OAB before BOTOX treatment, given by the mean number of daily leakages, equalled 4.8. The median interval between treatments was 210 days.
Patient characteristics in the real world were similar to those in the clinical trials, showing a high degree of external validity. Treatment intervals were longer in the real world than in clinical trials, indicating that treatment cost could be lower when patients are treated as observed in real-world clinical practice.
Scandinavian journal of urology. 2017 Jul 05 [Epub ahead of print]
Katarina Gralén, Caroline Elmér, Eva Broström, Rikard Althin, Lars Malmberg
a IHE , The Swedish Institute for Health Economics , Lund , Sweden., b Stockholm Urogynecological Clinic , Stockholm , Sweden., c Department of Urology , Skåne University Hospital , Malmö , Sweden.