The present study aimed to report the urodynamic data from 46 male patients who underwent an orthotopic N-shaped neobladder replacement following a radical cystectomy during a 12-month period and to provide urodynamic evidence for the improvement of this technique.
A total of 46 consecutive male patients underwent a radical cystectomy and orthotopic N-shaped neobladder substitution due to muscle-invasive bladder cancer. Uroflowmetry, cystometry and urethral pressure profilometry were analyzed at 3-12 months following the surgery. The mean pressure of the neobladders was < 15 cm H2O at volumes of < 400 ml and 22.4 cm H2O at 100% capacity at 6 months. The mean pressure of the contractions was < 40 cm H2O at 6 months. The mean filling pressure following the surgery at 3 months was higher compared with that at 6 months. No difference was observed at the other time-points. When comparing the 9- and 12-month urodynamic characteristics, no significant changes were observed in the cystometric capacity. The mean post-void residual (PVR) urine volume was 58 ml. A mean voiding peak of 16.2 ml/sec was obtained using the Valsalva maneuver. The daytime continence rate was 90% at 12 months while the night-time continence rate was 60%.
Written by:
Zhang Z, Qi H, Zhou R, Jin X. Are you the author?
Department of Urology, Qingdao Municipal Hospital, Qingdao, Shandong 266071, P.R. China; School of Medicine, Shandong University, Jinan, Shandong 250012, P.R. China.
Reference: Oncol Lett. 2013 Oct;6(4):1053-1056.
doi: 10.3892/ol.2013.1502
PubMed Abstract
PMID: 24137463
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