A novel operative procedure for pelvic organ prolapse utilizing a MRI-visible mesh implant: Safety and outcome of modified laparoscopic bilateral sacropexy - Abstract

Introduction: Sacropexy is a generally applied treatment of prolapse, yet there are known possible complications of it.

An essential need exists for better alloplastic materials.

Methods: Between April 2013 and June 2014, we performed a modified laparoscopic bilateral sacropexy (MLBS) in 10 patients using a MRI-visible PVDF mesh implant. Selected patients had prolapse POP-Q stages II-III and concomitant OAB. We studied surgery-related morbidity, anatomical and functional outcome, and mesh-visibility in MRI. Mean follow-up was 7.4 months.

Results: Concomitant colporrhaphy was conducted in 1/10 patients. Anatomical success was defined as POP-Q stage 0-I. Apical success rate was 100% and remained stable. A recurrent cystocele was seen in 1/10 patients during follow-up without need for intervention. Out of 6 (6/10) patients with preoperative SUI, 5/6 were healed and 1/6 persisted. De-novo SUI was seen in 1/10 patients. Complications requiring a relaparoscopy were seen in 2/10 patients. 8/10 patients with OAB were relieved postoperatively. The first in-human magnetic resonance visualization of a prolapse mesh implant was performed and showed good quality of visualization.

Conclusion: MLBS is a feasible and safe procedure with favorable anatomical and functional outcome and good concomitant healing rates of SUI and OAB. Prospective data and larger samples are required.

Written by:
Joukhadar R, Meyberg-Solomayer G, Hamza A, Radosa J, Bader W, Barski D, Ismaeel F, Schneider G, Solomayer E, Baum S.   Are you the author?
Department of Obstetrics and Gynecology, University Hospital Homburg, Kirrberger Straße 100, 66424 Homburg, Germany; Department of Obstetrics and Gynecology, Klinikum Bielefeld, Teutoburger Straße 50, 33604 Bielefeld, Germany; Department of Urology, Lukaskrankenhaus GmbH, Preußenstraße 84, 41464 Neuss, Germany; Department of Gynecology, University Hospital Charité, Campus Virchow-Klinikum (CVK), Mittelallee 9, 13353 Berlin, Germany; Department of Radiology, University Hospital Homburg, Kirrberger Straße 100, 66424 Homburg, Germany.

Reference: Biomed Res Int. 2015;2015:860784.
doi: 10.1155/2015/860784


PubMed Abstract
PMID: 25961042

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