Objective: To investigate the characteristics of modified Oxford grading scale (MOS) and pelvic floor surface electromyography (sEMG) based on Glazer protocol in patients with stress urinary incontinence (SUI), and analyze the correlation between the two methods. Methods: This study was a cross-sectional survey. A total of 212 subjects in May 2019 were enrolled and divided into SUI group (n=61) and non-SUI group (n=151) based on the commonly used 3 incontinence questions (3IQ). MOS test and sEMG parameters were measured by the same rehabilitator. The sEMG parameters included the mean and variation coefficient in the prerest phase, the maximum and relaxation time of 5 rapid contractions, the mean and variability of EMG in 10 s tonic contraction phase, the mean and variability of EMG in 60 s endurance contraction phase, and the mean and variability of EMG in postrest phase. The differences of the above parameters between SUI group and non-SUI group were compared, the logistic regression and Spearman method were used to analyze the correlation between MOS and sEMG parameters. Results: The prevalence of SUI was 28.8%(61/212) in community, body mass index and delivery mode were the risk factors (all P<0.05). The MOS of the SUI group and the non-SUI group were 3 (2,3) and 3 (3,4), respectively, with significant difference (Z=-2.58, P=0.010). Among the sEMG parameters of SUI group and non-SUI group, the maximum values of phasic contractions were 23.12 (13.65, 37.89), 30.68 (20.28, 47.02) μV, the mean of tonic contractions were 14.32 (9.62, 21.49), 17.65 (12.05, 26.35) μV, and the mean of endurance contractions were 12.78(7.88, 18.76), 16.55(11.13, 22.40) μV, respectively, with statistical significance (Z=-2.34, -2.37, -3.20, all P<0.05). The multivariate logistic regression revealed that both the variation coefficient of tonic contractions (OR=157.86, 95%CI: 1.99-12 595.51, P<0.05) and the amplitude of endurance contractions(OR=1.11, 95%CI: 1.03-1.19, P<0.05) were correlated with SUI. The tonic contractions amplitude had the tendency to be related to SUI (OR=0.95, 95%CI: 0.09-1.00, P<0.05). In all subjects, MOS was correlated with the maximum value of rapid contractions, average value of tonic contractions and average value of endurance contractions (r=0.516, 0.503, 0.464, all P<0.05). In SUI group (r=0.510, 0.442, 0.385, all P<0.05), and non-SUI group (r=0.495, 0.524, 0.488, all P<0.05), MOS was correlated with the above parameters. Conclusions: MOS and sEMG based on Glazer protocol indicate that the contractility of pelvic floor muscle decreases in SUI patients. The results of sEMG and MOS are consistent, which can be used for quantitative evaluation of pelvic floor muscle function in SUI patients.
目的： 探讨压力性尿失禁（SUI）患者改良牛津肌力分级（MOS）和基于Glazer评估的盆底表面肌电（sEMG）参数的特征，分析两种检测方法的相关性。 方法： 本研究为横断面调查研究。选取2019年5月社区查体人群共212例，基于国际上常用的尿失禁简易诊断问卷，将受试者分为SUI组（n=61）和非SUI组（n=151）。由同一名康复师进行MOS测试以及sEMG参数检测，评估参数包括前静息阶段肌电均值和变异性、5次快速收缩阶段肌电最大值和放松时间、10 s持续收缩阶段肌电均值和变异性、60 s耐力收缩阶段肌电均值和变异性、后静息阶段肌电均值和变异性。比较SUI组和非SUI组上述参数的差异，采用logistic回归法和Spearman法进行MOS和sEMG参数的相关分析。 结果： 社区人群中SUI患病率为28.8%（61/212），其中体质指数和分娩方式为SUI的危险因素（均P<0.05）。SUI组和非SUI组MOS分别为3（2，3）、3（3，4）级，差异有统计学意义（Z=-2.58，P=0.010）。SUI组和非SUI组sEMG参数中，快速收缩阶段最大值分别为23.12（13.65，37.89）、30.68（20.28，47.02）μV，紧张收缩阶段平均值分别为14.32（9.62，21.49）、17.65（12.05，26.35）μV，耐力收缩阶段平均值分别为12.78（7.88，18.76）、16.55（11.13，22.40）μV，差异均有统计学意义（Z=-2.34、-2.37、-3.20，均P<0.05）。多因素logistic回归分析提示紧张收缩阶段变异性（OR=157.86，95%CI：1.99~12 595.51，P<0.05）以及耐力收缩阶段平均值（OR=1.11，95%CI：1.03~1.19，P<0.05）与SUI相关，紧张收缩阶段平均值与SUI也有相关趋势（OR=0.95，95%CI：0.09~1.00，P<0.05）。在全部受试者中，MOS和快速收缩阶段最大值、紧张收缩阶段平均值以及耐力收缩阶段平均值存在相关性（r=0.516、0.503、0.464，均P<0.05）。在SUI组（r=0.510、0.442、0.385，均P<0.05）、非SUI组（r=0.495、0.524、0.488，均P<0.05），MOS与上述参数均存在相关性。 结论： MOS和基于Glazer评估的sEMG均提示SUI患者盆底肌收缩力下降。sEMG与MOS结果一致，可用于SUI患者盆底肌功能的量化评估。.
Zhonghua yi xue za zhi. 2020 Oct 13 [Epub]
J Chen, Y Ren, L Zhu
Department of Obstetrics & Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Beijing 100730, China.