The Clinical Effects of Pixel CO2 Laser on Bladder Neck and Stress Urinary Incontinence.

Our study aims to assess Pixel CO2 laser efficacy for female stress urinary incontinence (SUI).

In the study, 25 women with SUI were included and scheduled for vaginal Pixel CO2 Laser (FemiLift™, Alma Lasers, Israel) treatment. All subjects had a baseline and 6-month post-treatment assessment that included three-dimensional perineal ultrasound and validated questionnaires.

Data showed that monthly three-session vaginal Pixel CO2 Laser treatment significantly improved SUI symptoms, as evidenced by validated questionnaires, including UDI-6, IIQ-7, ICIQ, and vaginal laxity questionnaire (p < 0.05). The Pixel CO2 Laser efficacy in vaginal treatment was 20/25 (80%), and the perineal sonography showed that laser treatment significantly decreased bladder neck mobility and middle urethral area (during resting and straining). Permanent adverse events were not found.

The results of our study suggested that for the treatment of mild to moderate SUI symptoms, Pixel CO2 Laser is effective and safe; however, more studies and a longer follow-up should be conducted to confirm its efficacy and durability.

Journal of clinical medicine. 2022 Aug 24*** epublish ***

Cheng-Yu Long, Jennifer Po-Ning Lee, Zi-Xi Loo, Yi-Yin Liu, Chang-Lin Yeh, Chien-Wei Feng, Kun-Ling Lin

Department of Obstetrics and Gynecology, Kaohsiung Medical Hospital, Kaohsiung Medical University, Kaohsiung 80708, Taiwan., Vaginal Rejuvenation & Regenerative Center, Vigor Aesthetic Medical Group, Kaohsiung 81358, Taiwan., Department of Obstetrics and Gynecology, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung Medical University, Kaohsiung 80145, Taiwan., Department of Obstetrics and Gynecology, Kaohsiung Municipal Siao-Gang Hospital, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.