Understanding treatment impact on quality of life of patients with stress urinary incontinence (SUI) in the short- and long-term is vital to optimizing treatment success.
This study aimed to report 36-month patient satisfaction and quality of life results from a 522 study of single-incision and full-length slings in SUI.
This was a secondary analysis of the Altis 522 study, a prospective, multicenter, nonrandomized, noninferiority cohort study comparing the Altis single-incision sling to full-length slings for the treatment of SUI. The current study endpoints are patient-reported outcomes on quality of life related to continence status at 6, 12, 18, 24, and 36 months, measured through patient-reported, validated questionnaires: Urogenital Distress Inventory, Incontinence Impact Questionnaire, Patient Global Impression of Improvement, and Surgical Satisfaction Questionnaire.
A total of 355 women underwent the sling procedure (184, Altis group; 171, comparator group). At 36 months, 140 (76.0%) of Altis and 101 (59.1%) of comparator group patients were assessed. Patient Global Impression of Improvement at 36 months indicated that 92.9% of Altis and 90.1% of comparator patients reported that their condition was "very much better" or "much better" (P = 0.444). Urogenital Distress Inventory at 36 months indicated improvement in quality of life in both groups with a mean change from baseline of 41.7 ± 19.3 (Altis group; n = 140) versus 44.4 ± 22.2 (comparator group; n = 101) (P = 0.305). The Incontinence Impact Questionnaire indicated average quality-of-life improvement of 50% in both groups from presurgery to 36 months, with a mean change from baseline of 51.8 ± 25.8 (Altis group) versus 50.2 ± 25.1 (comparator group) (P = 0.619).
This 36-month study demonstrated the lasting, positive effect that surgical intervention can have on patients with SUI.
Urogynecology (Philadelphia, Pa.). 2024 Oct 18 [Epub ahead of print]
Ty Erickson, Edward Gheiler, Craig E Hanson, Rebecca McCrery, Mitesh Parekh, Mohamad Parva, Le Mai Tu
From the Department of Gynecology, UNLV School of Medicine, Las Vegas, NE;., Department of Urology, Nova Southeastern University/Urological Research Network LLC, Hialeah, FL., Department of Urogynecology, Van Wert Health, Van Wert, OH., Department of Gynecology, Adult and Pediatric Urology and Urogynecology, Omaha, NE., Department of Obstetrics and Gynecology, Ohio University College of Medicine, Athens, OH., Department of Gynecology, The Group for Women, Tidewater Clinical Research, Norfolk, VA., Department of Surgery, Division of Urology, Hospital Center, University of Sherbrooke, Sherbrooke, Quebec, Canada.