Long-term follow-up and success rate of ventral inlay buccal mucosal graft urethroplasty for female urethral stricture disease.

To determine the long-term success of ventral inlay buccal-mucosal graft urethroplasty (Vi-BMGU) for female urethral strictures (FUS).

We performed a retrospective analysis of prospectively maintained data on patients who underwent Vi-BMGU between May 2016 and January 2020 with a minimum follow-up of 2 years. The primary outcome was the long-term success after 2 to 5 years of surgery. Patients were followed with American Urological Association (AUA) symptom score, uroflowmetry, and post-void residual (PVR) urine measurement. Failure (recurrence) was defined by an increase in the AUA symptoms score by 3 on subsequent follow-up visits and Qmax <12cc/s and inability to calibrate with an 18 Fr catheter.

Twenty-one patients were included. The Median follow-up was 42 months (range: 24-64 months). The AUA symptom scores, Qmax, and PVR, improved in all except three patients. The median AUA score fell from 27 (range 18-34) at diagnosis to 9 (range 6-24), at the last follow-up. Similarly, the median PVR values decreased from 138 ml (34-290) to 24 ml (19-360) and the mean Qmax improved from 7.7±2.2 ml/s to 22.6±5 ml/s. None experienced urinary incontinence. There were two failures, one at six months and the other at 24 months. The overall success rate was 90.5 %. Success rates on life table analysis were 95%, 85%, 85%, 85%, and 85% after 1,2,3,4 and 5 years respectively.

The 95% success at 1 year and 85% sustained success at 2 to 5 years of follow-up establishes the long-term success of Vi-BMGU.

Urology. 2022 May 16 [Epub ahead of print]

Santosh Kumaraswamy, Swarnendu Mandal, Manoj K Das, Prasant Nayak

MS General Surgery, Senior Resident(M.Ch. urology), Department of Urology, AIIMS, Bhubaneshwar. Electronic address: ., M.Ch. Urology, Assistant Professor, Department of Urology, AIIMS, Bhubaneshwar. Electronic address: ., M.Ch. Urology, Assistant Professor, Department of Urology, AIIMS, Bhubaneshwar. Electronic address: ., M. Ch. Urology, Additional Professor and Head of the department, Department of Urology, AIIMS, Bhubaneshwar. Electronic address: .