Although weight loss is known to alleviate urinary incontinence (UI) symptoms, the effects of sex and body size on this relationship remain insufficiently explored.
We analyzed data from the National Health and Nutrition Examination Survey (NHANES) 2007-2018, comprising 28,161 participants. Weighted logistic regression analysis, fitted curves, and subgroup analysis were used to assess the association between the percentage of weight loss and UI. Propensity score matching (PSM) was performed to account for potential confounding factors.
After PSM, multivariate logistic regression showed an inverse relationship between weight loss percentage and UI risk (odds ratio [OR] = 0.97, 95% confidence interval [CI]: 0.94-0.99). Compared with weight loss percentages < 0%, the risk of UI significantly decreased with weight loss percentages > 5% (weight loss percentage 5.1-10%: OR = 0.83, 95% CI: 0.70-1.00; weight loss percentage 10.1-15%: OR = 0.73, 95% CI: 0.55-0.97; weight loss percentage > 15%: OR = 0.52, 95% CI: 0.39-0.70). Furthermore, subgroup analysis indicated that this relationship was more significant in males and non-overweight/non-obese populations.
There was an inverse relationship between weight loss percentage and UI risk, with noticeable differences based on sex and body size. However, these findings warrant further investigation.
World journal of urology. 2024 Nov 02*** epublish ***
Feng Chen, Hao Lin, Yuansi Zhang, Yu Zhang, Maoping Chu, Lulu Pan
Children's Heart Center, The Second Affiliated Hospital and Yuying Children's Hospital, Institute of Cardiovascular Development and Translational Medicine, Wenzhou Medical University, Wenzhou, Zhejiang Province, PR China., Department of Gastroenterology, Pingyang Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, PR China., Department of Traditional Chinese Medicine, Wenzhou Yebo Proctology Hospital, Wenzhou, Zhejiang Province, PR China., Department of Child Healthcare, Wenzhou People's Hospital, Wenzhou, Zhejiang Province, PR China., Children's Heart Center, The Second Affiliated Hospital and Yuying Children's Hospital, Institute of Cardiovascular Development and Translational Medicine, Wenzhou Medical University, Wenzhou, Zhejiang Province, PR China. ., Department of Child Healthcare, Wenzhou People's Hospital, Wenzhou, Zhejiang Province, PR China. .