4th ICI Lecture Series: Vesico-vaginal fistula in the developing world (Committee 18)

Presented by Dirk DeRidder, MD, et al., at the Fourth International Consultation on Incontinence (ICI) - July 5 - 8, 2008. Palais des Congres, Paris, France.



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This presentation reflects a work-in-progress, and the science contained herein
will be published in textbook format at a future date.



 D. De Ridder Belgium 
G. Badlani USA 
A.Browning Ethiopia 
P. Singh India 
I. Sombie Burkina Faso 
L. Wall USA
 The evidence 
 Epidemiology 
 Etiology 
 Diagnosis 
 Classification 
 Treatment 
 Prevention 
 Organisation of fistula care 
 Recommandations
 Pubmed and Sumsearch 
â—¦515 articles 
ï‚– 149 published over the last 5 years 
ï‚– 8 trials 
ï‚– Mostly observational studies 
ï‚– Mostly by a small group of authors 
 All evidence levels 3 or 4 
 This is not a criticism but a challenge and even 
obligation for the scientific communities!!
 The evidence 
 Epidemiology 
 Etiology 
 Diagnosis 
 Classification 
 Treatment 
 Prevention 
 Organisation of fistula care 
 Recommandations
 Literature based estimates 
â—¦Prevalence: 2 million women 
â—¦Incidence: 10000-50000/y 
 Estimates by surgical centres 
â—¦Prevelant cases ( Northern Nigeria) 
â—¦Incidence ( Ethiopia, Tanzania) 
â—¦Proportion of pregnant women with fistula ( Pakistan) 
â—¦Proportion of married women with fistula (Bangladesh) 
 Population based surveys 
â—¦Western Africa , Bangladesh & Malawi
 Incidence 
â—¦Empirical estimate Vangeenderhuysen 2001 
ï‚– 124/100 000 in Sub-Saharan Africa 
â—¦Model-based estimate Abou Zahr 1998 
ï‚– 18.8/100 000 in Sub-Saharan Africa 
ï‚– Global 654000 of which 262000 in Sub-Saharan Africa 
 Prevalence 
â—¦Life time prevalence in Malawi 1/20    Johnson 2007 
â—¦1,5 / 1000 in 26819 interviewed women   Muleta 2007
The World Health Report 2005: Make every 
mother and child count, WHO Geneva, 2005 
Maternal mortality as surrogate risk indicator for obstetric fistula 
 WHO Monitoring of the struggle against fistula 
â—¦Epidemiologic 
ï‚– Incidence & prevalence 
ï‚– Estimated rate / 1000 deliveries 
â—¦Delivery of care 
ï‚– Persons with midwifery & cesarean skills/ 1000 births 
ï‚– Number of fistula centres 
ï‚– Number of fistula ( simple & complex) surgeons 
â—¦Training 
ï‚– Training facilities & number of surgeons trained 
â—¦Quality of care 
ï‚– Proportion of successfull closures,continence 
ï‚– Proportion of failed fistula repairs 
ï‚– Social reintegration 
L. Wall & De Bernis, 2006 
Prevention 
-incidence/prevalence 
-rate/1000 births 
-persons with skills 
…. 
Treatment 
-training facilities 
-surgeons trained 
….. 
Reintegration 
- Social reintegration 
Maulet 2007
Number of patients treated 
Nigeria 
Mohammad 2007 
0 
5 
10 
15 
20 
25 
30 
1999/00 2000/01 2001/02 2002/03 2003/04 2004/05 2005/06 
Years  
N 
um 
b 
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r 
 o 
f 
 f 
is 
tu 
la 
 c 
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ie 
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ts 
 
External funding stopped
 The evidence 
 Epidemiology 
 Etiology 
 Diagnosis 
 Classification 
 Treatment 
 Prevention 
 Organisation of fistula care 
 Recommandations
 The obstructed labor complex 
â—¦Delay in deciding to seek help 
â—¦Delay in arriving at the health care facility 
â—¦Delay in receiving adequate care 
 Injuries sustained during operative interventions 
â—¦Forceps, cesarean section in difficult conditions with 
subsequent complications 
 Sexual abuse, rape, accidents 
 Traditional practices 
â—¦Gishiri cutting, infibulation
Low socio-economic status of women  
 
 
 
 
Malnutrition                                  Limited social roles                          Illiteracy and lack of  
                                                                                                                   formal education      
 
 
Early marriage  
 
 
 
Childbearing before pelvic growth is complete  
 
 
Relatively large fetus  
or malpresentation                    Cephalopelvic disproportion  
 
 
 
Lack of access to emergency obstetric service s 
 
 
 
Obstructed labor  
 
 
                                                                                                    Harmful traditional practices

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