CHICAGO, IL USA (UroToday) - In this related ABC trial study, some women harbor urinary bacteria (microbiome) but the optimum levels of the bacterial status is not well understood. So the question was asked, “What is normal”?
The researchers used qPRC to quantify the ABC participants. All of the results were generated at a single lab at Loyola University. The 16SrRNA gene was used as the molecular monitor because mutations occur at a slow but constant rate. Of the 155 participants in the study (62% of all ABC participants), 40% of these subjects had urinary bacteria in their bladders. Could this bacteria be protective of UTI? Among UUI patients, clinical urine cultures do not fully predict symptomatic UTI.
Future studies are needed to further study DNA sequencing, better identifying this type of bacteria and why the microbiome are there.
Overall, the researchers concluded in this study group undergoing UUI treatment that the presence of a baseline urinary microbiome is associated with a reduced risk for UTI.
Presented by L. Brubaker* at the annual American Urogynecologic Society (AUGS) 33rd Annual Scientific Meeting - October 3 - 6, 2012 - Hilton Chicago - Chicago, Illinois USA
* Strich School of Medicine, Loyola University, Chicago, IL USA
Reported for UroToday by Karen Roberts, Medical Editor
This year’s 33rd Annual Meeting of the American Urogynecologic Society (AUGS) is the largest gathering to date with an increase in abstracts (346) and video presentations (41). AUGS reports an overall membership increase at 1,500 members.
