AIMS: To identify women with diabetes at risk of increased postvoid residual volume (PVR) and investigate the relationship of increased PVR to urinary symptoms in women with diabetes.
METHODS: PVR was measured by bladder ultrasonography in a cross-sectional cohort of 427 middle-aged and older women with diabetes. Participants completed questionnaires assessing urgency incontinence, stress incontinence, daytime frequency, nocturia, obstructive voiding, and diabetes-related end-organ complications: heart disease, stroke, neuropathy. Serum HbA1c and creatinine were recorded.
RESULTS: 75% of participants had a PVR of 0-49, 13% had a PVR of 50-99, and 12% had a PVR ≥ 100mL. Approximately 59% of women with a PVR< 50mL reported at least one lower urinary tract symptom. Women with diabetes and a PVR ≥ 100mL were more likely to report urgency incontinence (OR 2.18, CI 1.08-4.41) and obstructive voiding symptoms (OR 2.47, CI 1.18-5.17) than women with PVR< 50mL. In multivariable models, poorer glycemic control was associated with an increased likelihood of PVR ≥ 100mL (OR 1.30, CI 1.06-1.59 per 1.0-U increase in HbA1c).
CONCLUSIONS: PVR volumes ≥ 100mL may indicate increased risk of urgency incontinence and obstructive voiding. Glycemic control may play a role in preventing increased PVR in women with diabetes.
Written by:
Appa AA, Brown JS, Creasman J, Van Den Eeden SK, Subak LL, Thom DH, Ferrara A, Huang AJ. Are you the author?
University of California, San Francisco, United States.
Reference: Diabetes Res Clin Pract. 2013 Jun 14. pii: S0168-8227(13)00191-5.
doi: 10.1016/j.diabres.2013.05.005
PubMed Abstract
PMID: 23773505
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