Introduction: Overactive bladder (OAB) and its resultant urge urinary incontinence (UUI) are significant problems that medically, psychologically and financially affect people.
The constellation of symptoms comprising OAB affects ∼ 16% of the adult population and its prevalence increases with aging. The typical class of medications used to treat OAB is antimuscarinics.
Areas covered: OAB medications, with a focus on tolterodine for the treatment of UUI are reviewed. A thorough review of English language literature using EMBASE/Medline and PubMed has been performed.
Expert opinion: Tolterodine provides a reasonable starting point when treating patients with OAB and UUI. Efficacy and tolerability are generally comparable between tolterodine and other newer antimuscarinics. Tolterodine is a good option as part of the algorithm in the treatment of OAB and UUI.
Written by:
Elterman DS, Chughtai B, Kaplan SA, Barkin J. Are you the author?
Weill Cornell Medical College of Cornell University, James Buchanan Brady Department of Urology, 425 East 61st Street, 12th floor, New York, NY 10065, USA.
Reference: Expert Opin Pharmacother. 2013 Jul 26. Epub ahead of print.
doi: 10.1517/14656566.2013.823158
PubMed Abstract
PMID: 23885788
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