Paragangliomas are the neuroendocrine tumors which arise from the chromaffin cell.
Tumors arising from the adrenal medulla are known as pheochromocytomas, while others originating from the extra-adrenal site are known as extra-adrenal paragangliomas. Paraganglioma can be multifocal which can arise synchronously or metachronously. Paragangliomas are less functionally active than the pheochromocytomas; they secrete noradrenaline and rarely dopamine, while adrenal pheochromocytomas secrete adrenaline or nor-adrenaline. Nonfunctional multifocal paragangliomas are very rare. We report a case of a 45-year-old female with multifocal nonfunctional paragangliomas of the retroperitoneum and urinarybladder which were surgically removed, and the diagnosis was confirmed on histopathology.
Written by:
Sherwani P, Anand R, Narula MK, Siddiqui AA, Aggarwal S. Are you the author?
Department of Radiodiagnosis, Lady Hardinge Medical College and Associated Hospitals, New Delhi, India; Department of Surgery, Lady Hardinge Medical College and Associated Hospitals, New Delhi, India; Department of Pathology, Lady Hardinge Medical College and Associated Hospitals, New Delhi, India.
Reference: Indian J Radiol Imaging. 2015 Apr-Jun;25(2):198-201.
doi: 10.4103/0971-3026.155879
PubMed Abstract
PMID: 25969646