APOBEC-mediated Mutagenesis as a Likely Cause of FGFR3 S249C Mutation Over-representation in Bladder Cancer
Ming-Jun Shi a,b,i,y , Xiang-Yu Meng a,b,c,y , Philippe Lamy d,y , A. Rouf Banday e,y , Jie Yang f , Aura Moreno-Vega a,b , Chun-Long Chen g,h , Lars Dyrskjøt d,z , Isabelle Bernard-Pierrot a,z , Ludmila Prokunina-Olsson e,z , Franc¸ ois Radvanyi a,z, a Institut Curie, CNRS, UMR144, Molecular Oncology team, PSL Research University, Paris, France; b Paris-Sud University, Paris-Saclay University, Paris, France; cDepartment of Urology, Zhongnan Hospital, Wuhan University, Wuhan, China; dDepartment of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark; e Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA; f Inserm UMR-1162, Génomique fonctionnelle des Tumeurs solides, Université Paris Diderot, Paris, France; g Institut Curie, CNRS, UMR3244, PSL Research University, Paris, France; h Sorbonne Université, Paris, France; i Department of Urology, Beijing Friendship Hospital, Capital Medical University, Beijing, China
Shi M-J, et al. APOBEC-mediated Mutagenesis as a Likely Cause of FGFR3 S249C Mutation Overrepresentation in Bladder Cancer. Eur Urol (2019), https://doi.org/10.1016/j.eururo.2019.03.032
Read an Expert Commentary by Bishoy M. Faltas, MD