Does intravesical BCG for bladder cancer protect from COVID-19?

The study aimed to correlate the history of intravesical BCG as well as infantile BCG immunization with the incidence and severity of COVID-19 infection.

Retrospective data collection of patients with high-risk non muscle invasive bladder cancer (NMIBC) from two Canadian centers. Data collection included a history of BCG instillation, infantile immunization, and the development of COVID-19 infection. Admission and/ or mortality because of COVID-19 was reported.

We could include data from 348 patients: including 188 and 160 patients from Ontario and British Columbia respectively. COVID-19 affected 15% of these patients. Intravesical BCG was used in 44% of these patients. Intravesical BCG and/or infantile BCG immunization did not correlate with the incidence of COVID-19 infection.

Previous intravesical BCG and/ or a history of infantile BCG vaccination were not more/ less frequent in patients who had COVID-19 infection.

Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica. 2024 May 09 [Epub ahead of print]

Anastasia MacDonald, Lexia Bao, Vahid Mehrnoush, Asmaa Ismail, Livio Di Matteo, Ahmed Zakaria, Hazem Elmansy, Peter Black, Ahmed Kotb

Department of Urology, Northern Ontario School of Medicine University, Thunder Bay, ON. ., Department of Urology, University of British Columbia, BC. ., Department of Urology, Northern Ontario School of Medicine University, Thunder Bay, ON. ., Department of Urology, Northern Ontario School of Medicine University, Thunder Bay, ON. ., Department of Economics, Lakehead University, Thunder Bay, ON. ., Department of Urology, Northern Ontario School of Medicine University, Thunder Bay, ON. ., Department of Urology, Northern Ontario School of Medicine University, Thunder Bay, ON. ., Department of Urology, University of British Columbia, BC. ., Department of Urology, Northern Ontario School of Medicine University, Thunder Bay, ON. .