Penile cancers are uncommon and should be treated in expert center. Radiotherapy indications are mainly limited to exclusive brachytherapy for early stage penile glans cancer. Brachytherapy yields to excellent outcome for disease control and organ and function preservation. Only scarce data are available for external beam radiation therapy. It could be considered as palliative setting for irradiation of the primary tumor. For lymph node irradiation, external beam radiation therapy (with or without chemotherapy) could be discussed either as neoadjuvant approach prior to surgery for massive inguinal lymph node invasion or as adjuvant approach in case of high-risk of relapse. However, these cases should be discussed on an individual basis, as the level of evidence is poor. We present the recommendations of the French Society of Oncological Radiotherapy on the indications and techniques for external beam radiotherapy and brachytherapy for penile glans cancer.
Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique. 2021 Dec 20 [Epub ahead of print]
A Escande, D Peiffert, C Dejean, J-M Hannoun-Lévi, A Cordoba, P Pommier, C Haie-Méder, C Chargari
Département de radiothérapie, centre Oscar-Lambret, 3, avenue Frédéric-Combemale, 59000 Lille, France; Faculté de médecine Henri-Warembourg, université de Lille, 59000 Lille, France; Laboratoire Cristal, UMR 9189, 59009 Villeneuve-d'Ascq, France. Electronic address: ., Département d'oncologie radiothérapie, institut de cancérologie de Lorraine centre Alexis-Vautrin, 6, avenue de Bourgogne, 54519 Vandœuvre-lès-Nancy, France., Département d'oncologie radiothérapie, centre Antoine-Lacassagne, 33, avenue de Valombrose, 06000 Nice, France., Département de radiothérapie, centre Oscar-Lambret, 3, avenue Frédéric-Combemale, 59000 Lille, France., Département d'oncologie radiothérapie, centre Léon-Bérard, 28, rue Laennec, 69373 Lyon cedex 08, France., Département d'oncologie radiothérapie, centre de cancérologie, Charlebourg la Défense, 65, avenue Foch, 92250 La Garenne Colombes, France., Département d'oncologie radiothérapie, Gustave-Roussy Cancer Campus, 114, rue Édouard-Vaillant, 94800 Villejuif, France; École du Val-de-Grâce, boulevard de Port-Royal, 75005 Paris, France; Département des effets biologiques des rayonnements, institut de recherche biomédicale des armées, 91223 Brétigny-sur-Orge, France.