Lower extremity lymphedema is a major source of morbidity in up to 70% of penile cancer patients. Lymphedema is often thought to be incurable, though surgical treatments have started to emerge. This study is the first to apply lymphovenous bypass specifically to penile cancer patients status post lymphadenectomy.
We performed microsurgical lymphovenous bypass in 3 patients who underwent inguinal lymphadenectomy for advanced penile cancer, and later lymph node transplant in 1 patient.
The lymphovenous bypass was performed by a trained microsurgeon: Two patients were treated as outpatients for lymphedema, and 1 patient underwent prophylactic lymphovenous bypass simultaneously with initial lymphadenectomy. We saw significant improvement in patient's clinical lymphedema as well as lymphatic drainage on infared imaging for 2 of 3 patients at 12 months, however 1 of these patients did require later lymph node transfer at 24 months.
This early proof of concept study shows that these procedures should be considered and studied further in the treatment and prevention of debilitating lymphedema in the penile cancer population.
Urologic oncology. 2022 Jan 15 [Epub ahead of print]
Charlotte Goldman, Harry Lee, Laura Tom, Ross Krasnow
MedStar Georgetown University Hospital Department of Urology, Washington, DC. Electronic address: ., Georgetown University School of Medicine, Washington, DC., MedStar Washington Hospital Center Department of Plastic Surgery, Washington, DC., MedStar Washington Hospital Center Department of Urology, Washington, DC.