Non-human papillomavirus penile squamous cell carcinoma with unusual coral-like polymorphic lesion.

Penile cancer is a rare malignancy of the male genital system. Approximately 98% of penile cancer corresponds to squamous cell carcinoma (SCC), with further morphological and molecular classification into human papillomavirus (HPV) dependent and non-HPV SCC. Compared to HPV-induced SCC, non-HPV SCC appeared to have a worse prognosis. Here, we present a case of an uncircumcised male with an unusual coral-like polymorphic lesion, and confirmed histopathology of well-differentiated non-HPV penile SCC with rapid growth progression.

Urology annals. 2023 Jul 17 [Epub]

Sherryn Sherryn, I Putu Gde Sanjaya, Luh Dewi Rahayu

Department of Clinical Medicine, Universitas Cenderawasih, Jayapura, Papua, Indonesia., Department of Urology, Mangusada General Hospital (RSD Mangusada), Badung, Bali, Indonesia., Department of Pathology, Mangusada General Hospital (RSD Mangusada), Badung, Bali, Indonesia.