Primary high-grade serous carcinoma arising in the urethra or urethral diverticulum: A report of 2 cases of an extremely rare phenomenon - Abstract

Serous carcinomas most commonly arise within the uterine corpus or ovary/fallopian tube, but there are 2 prior case reports of primary vaginal serous carcinoma.

We report 2 examples of high-grade serous carcinoma arising within the urethra or a urethral diverticulum (1 case each). Both neoplasms exhibited the classic morphologic features of high-grade serous carcinoma, and a combination of clinical, radiologic, and pathologic examination excluded other possible sites of primary neoplasm.

Written by:
Flynn C, Oxley J, McCullagh P, McCluggage WG.   Are you the author?
Departments of Pathology, Belfast Health and Social Care Trust, Belfast, Northern Ireland Southmead Hospital, Bristol Royal Devon and Exeter NHS Foundation Trust, Exeter, England.

Reference: Int J Gynecol Pathol. 2013 Jan;32(1):141-5.
doi: 10.1097/PGP.0b013e318253c71b


PubMed Abstract
PMID: 23202781

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