Objective: The aim of this study was to determine whether a higher body mass index (BMI) in penile cancer patients is associated with more advanced penile cancer stage at the time of treatment and cancer survival.
Methods: We evaluated 433 penile cancer patients treated between 2006 and 2012 at our institute and recorded American Joint Committee on Cancer (AJCC) stage, BMI, circumcision, smoking and age. A proportional odds model was used to assess a possible association between BMI and AJCC stage at diagnosis and controlled for circumcision, smoking and age. Five-year disease-specific survival was calculated using the Kaplan-Meier method, with the log-rank test assessing equality of distributions.
Results: 433 patients with a mean BMI of 26.8 kg/m2 were analyzed. No statistically significant association between BMI and AJCC stage was found (odds ratio 1.01 per 1 kg/m2 increase in BMI, 95% confidence interval 0.97-1.05, p = 0.63). Differences in disease-specific survival were not observed based on the different BMI classes.
Conclusions: No association between BMI of penile cancer patients and their disease stage at the time of treatment was observed. Thus, BMI at penile cancer treatment does not affect prognosis
Written by:
Djajadiningrat RS, van Werkhoven E, Horenblas S. Are you the author?
Department of Urology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Reference: Urol Int. 2015 Jan 20. Epub ahead of print.
doi: 10.1159/000367927
PubMed Abstract
PMID: 25612647