Secondary malignancy of the penis is a rare clinical condition, often associated with disseminated genitourinary malignancies. The prognosis is poor and the treatment options include penectomy, local surgical excision, radiation therapy, chemotherapy and supportive therapy.
Neither of these therapeutic options lead to superior treatment outcomes in the literature. The authors report the case of a 66 year-old man with a metastasis to the glans penis from a rectal adenocarcinoma, diagnosed two years after radical treatment for primary disease. The patient underwent palliative treatment with radiotherapy and chemotherapy, remaining asymptomatic and disease-free at one year follow-up. Close follow-up of patients with history of rectal adenocarcinoma is very important. Radiochemotherapy is a feasible and effective therapeutic option for penile metastasis, addressing both disease control and symptomatic improvement.
Abstract available from the publisher.
Acta médica portuguesa. 2015 Aug 31 [Epub]
Beatriz Nunes, Margarida Matias, António Alves, Marília Jorge
Serviço de Radioterapia. Hospital de Santa Maria. Centro Hospitalar Lisboa Norte. Lisboa. Portugal. , Serviço de Oncologia Médica. Hospital de Santa Maria. Centro Hospitalar Lisboa Norte. Lisboa. Portugal. , Serviço de Anatomia Patológica. Hospital de Santa Maria. Centro Hospitalar Lisboa Norte. Lisboa. Portugal. , Serviço de Radioterapia. Hospital de Santa Maria. Centro Hospitalar Lisboa Norte. Lisboa. Portugal.