The Role of Imaging in Prostate Cancer Care Pathway: Novel Approaches to Urologic Management Challenges Along Ten Imaging Touch Points

We map out a typical prostate cancer care pathway through discussion of updates on modern imaging. Multiparametric MRI (mpMRI) is the most sensitive and specific imaging tool for diagnosis and local staging, transrectal ultrasound remains the most widely used technique for prostate biopsy guidance, CT and bone scan are useful in initial staging and recurrence detection. Novel imaging techniques in ultrasound elastography and mpMRI allow for increased lesion detection sensitivity and have the potential to enhance biopsy, while the development of new PET radiotracers has great promise for improved detection of local and metastatic disease in patients with biochemical recurrence.

Urology. 2018 May 03 [Epub ahead of print]

Qian Li, Feixiang Xiang, Xueying Lin, Joseph R Grajo, Long Yang, Yufeng Xu, Yu Duan, Urvi Vyas, Mukesh Harisinghani, Umar Mahmood, Anthony E Samir

Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.. Electronic address: ., Department of Ultrasound, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.. Electronic address: ., Department of Ultrasound, Fujian Medical University Union Hospital, Fuzhou 350001, China.. Electronic address: ., Department of Radiology, Division of Abdominal Imaging, University of Florida College of Medicine, Gainesville, FL 32610, USA.. Electronic address: ., Department of Ultrasound, Henan Province People's Hospital, Zhengzhou 450003, China.. Electronic address: ., Department of Radiology, Peking University First Hospital, Beijing 100034, China.. Electronic address: ., Department of Medical Ultrasonics, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.. Electronic address: ., Product Management, BK Ultrasound, Peabody, MA 01960, USA.. Electronic address: ., Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.. Electronic address: ., Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.. Electronic address: ., Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. Electronic address: .