Digital frozen section of the prostate surface during radical prostatectomy: a novel approach to evaluate surgical margins.

Intra-operative tailoring of surgical dissection during radical prostatectomy (RP) can be performed with the help of either 3D-augmented reality or frozen section analysis [1]. The latter with the purpose of maximizing nerve-sparing (NS) RP has evolved into the NeuroSAFE, a dissection technique of the prostatic surface limited to the neurovascular(NV)-structure-adjacent-prostatic-tissue aiming to detect cancer persisting at the NV-area [2].

BJU international. 2020 May 13 [Epub ahead of print]

Bernardo Rocco, Maria Chiara Sighinolfi, Alessia Cimadamore, Luca Reggiani Bonetti, Laura Bertoni, Stefano Puliatti, Ahmed Eissa, Valentina Spandri, Paola Azzoni, Eoin Dinneen, Gregg Shaw, Senthil Nathan, Salvatore Micali, Giampaolo Bianchi, Antonino Maiorana, Giovanni Pellacani, Rodolfo Montironi

Department of Urology, University of Modena and Reggio Emilia, Modena, Italy., Department of Pathology, Ospedale Policlinico e Nuovo Ospedale Civile S.Agostino Estense Modena, University of Modena and Reggio Emilia, Modena, Italy., Department of Pathological Anatomy, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Ancona, Italy., Department of Surgical, Medical, Dental and Morphological Sciences with Interest transplant, Oncological and Regenerative Medicine, University of Modena and Reggio Emilia, Modena, Italy., Department of Urology, University College Hospital London, London, UK., Department of Dermatology, University of Modena and Reggio Emilia, Modena, Italy.