PSMA PET/CT: joint EANM procedure guideline/SNMMI procedure standard for prostate cancer imaging 2.0.

Here we aim to provide updated guidance and standards for the indication, acquisition, and interpretation of PSMA PET/CT for prostate cancer imaging. Procedures and characteristics are reported for a variety of available PSMA small radioligands. Different scenarios for the clinical use of PSMA-ligand PET/CT are discussed. This document provides clinicians and technicians with the best available evidence, to support the implementation of PSMA PET/CT imaging in research and routine practice.

European journal of nuclear medicine and molecular imaging. 2023 Jan 05 [Epub ahead of print]

Wolfgang P Fendler, Matthias Eiber, Mohsen Beheshti, Jamshed Bomanji, Jeremie Calais, Francesco Ceci, Steve Y Cho, Stefano Fanti, Frederik L Giesel, Karolien Goffin, Uwe Haberkorn, Heather Jacene, Phillip J Koo, Klaus Kopka, Bernd J Krause, Liza Lindenberg, Charles Marcus, Felix M Mottaghy, Daniela E Oprea-Lager, Joseph R Osborne, Morand Piert, Steven P Rowe, Heiko Schöder, Simon Wan, Hans-Jürgen Wester, Thomas A Hope, Ken Herrmann

Department of Nuclear Medicine, University of Duisburg-Essen and German Cancer Consortium (DKTK)-University Hospital Essen, Hufelandstraße 55, 45147, Essen, Germany., Department of Nuclear Medicine, Klinikum Rechts Der Isar, Technical University of Munich, Munich, Germany., Division of Molecular Imaging & Theranostics, Department of Nuclear Medicine, University Hospital Salzburg, Paracelsus Medical University, Salzburg, Austria., Institute of Nuclear Medicine, UCLH NHS Foundation Trust, London, UK., Ahmanson Translational Theranostics Division, Department of Molecular and Medical Pharmacology, University of California Los Angeles, Los Angeles, CA, USA., Division of Nuclear Medicine and Theranostics, IEO European Institute of Oncology, IRCCS, Milan, Italy., Department of Radiology, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA., IRCCS, AOU Bologna, Bologna, Italy., Department of Nuclear Medicine, University Hospital Düsseldorf, Medical Faculty, Heinrich-Heine-University and Department of Nuclear Medicine, University Hospital Heidelberg, Heidelberg, Germany., Department of Nuclear Medicine, Division of Nuclear Medicine and Molecular Imaging, University Hospital Leuven, KU Leuven, Louvain, Belgium., Department of Nuclear Medicine, University Hospital Heidelberg, Heidelberg, Germany., Dana-Farber Cancer Institute/Brigham and Women's Hospital, Boston, USA., Banner MD Anderson Cancer Center, Phoenix, AZ, USA., Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany., Department of Nuclear Medicine, University Medical Center, University of Rostock, Rostock, Germany., Molecular Imaging Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA., Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Emory University School of Medicine, Atlanta, GA, USA., Department of Nuclear Medicine, University Hospital RWTH Aachen University, Aachen, Germany., Department of Radiology & Nuclear Medicine, Amsterdam University Medical Centers, VU University Medical Center, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands., Department of Radiology, Division of Molecular Imaging and Therapeutics, Weill Cornell Medicine, New York, NY, USA., Department of Radiology, Division of Nuclear Medicine and Molecular Imaging, University of Michigan, Ann Arbor, MI, USA., Division of Nuclear Medicine and Molecular Imaging, The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Memorial Sloan-Kettering Cancer Center, New York, NY, USA., Pharmaceutical Radiochemistry, Technische Universität München, Walther-Meißner-Str. 3, 85748, Garching, Germany., Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA., Department of Nuclear Medicine, University of Duisburg-Essen and German Cancer Consortium (DKTK)-University Hospital Essen, Hufelandstraße 55, 45147, Essen, Germany. .