A 61-year-old man underwent a piflufolastat 18F prostate-specific membrane antigen (PSMA) PET/CT scan due to a rising prostate-specific antigen level. The scan noted a focal cortical erosion on the CT scan in the right anterolateral tibia, and the PET showed an SUVmax of 4. 08. A biopsy of this lesion revealed a chondromyxoid fibroma. This rare case of a PSMA PET-positive chondromyxoid fibroma illustrates the importance of radiologists and oncologists not to assume an isolated bone lesion on a PSMA PET/CT scan as a bone metastasis from prostate cancer.
Clinical nuclear medicine. 2023 Apr 05 [Epub ahead of print]
Albert Jang, Sydney A Caputo, Madeline E Hawkins, Joshua E Talbert, Oliver Sartor
From the Deming Department of Medicine, Tulane University School of Medicine., Tulane University School of Medicine., Tulane Cancer Center., Department of Radiology, Tulane University School of Medicine, New Orleans, LA.