A 75-year-old man with a history of previously treated localized prostate cancer and prostate-specific antigen of 4.86 ng/mL was referred for a 68Ga-prostate-specific membrane antigen PET/CT. PET imaging was reported to be negative. After subsequent review and re-read of the scan, prostate-specific membrane antigen imaging revealed uptake along the penile shaft (SUVmax of 14.7). MRI was compatible with tumor. Penile metastases from prostate cancer, although uncommon, do occur and readers are encouraged to distinguish penile metastatic uptake from residual urine in the urethra.
Clinical nuclear medicine. 2023 Jun 06 [Epub ahead of print]
Sydney A Caputo, Graham Blair, Madeline Hawkins, Kendra Harris, Oliver Sartor
From the Tulane University School of Medicine., Tulane Cancer Center, New Orleans, LA.