Prostate cancer (PC) is the second leading cause of cancer and the fifth cause of cancer-related death. This manuscript aims to determine the incidence, mortality, and Disability Adjusted Life Years (DALYs) trends of PC in the last 30 years in Latin America and Mexico.
We performed a cross-sectional analysis of a publicly available data set. Data regarding the burden of prostate cancer in 20 Latin-American countries, and the 32 states of Mexico, were retrieved from the Global Burden of Disease Study 2019. Collected information included incidence and mortality rates (per 100,000), as well as the DALYs as absolute numbers and rates (per 100,000) and the annual rates of change in rates from 1990 to 2019.
In Latin America in males aged 55 years or older, the mean incidence rate was 344 cases per 100,000. The number of deaths attributable to prostate cancer observed was 67,110 and the mean mortality rate was 210 per 100,000. The overall burden of disease was 1,120,709 DALYs and the contribution of years of life lost (YLL) was 91.7% ([Formula: see text] = 1,027,946). Mexico presented an incidence rate (279.6) and mortality (99.1) rate (per /100 thousand). In Mexico, 13 states had a DALYs' rate above the national mean (883 per 100,000) and the highest burden (1360 DALYs/100,000) were documented in the state of Guerrero (Southwestern Mexico).
Only two Latin-American countries (Brazil and Colombia) and eight states of Mexico showed a decreased trend about the rate of change of DALYs in the last 30 years.
International urology and nephrology. 2023 Jun 03 [Epub ahead of print]
Jose Guzman-Esquivel, Efren Murillo-Zamora, Monica Ortiz-Mesina, Hector R Galvan-Salazar, Luis De-Leon-Zaragoza, Juan C Casarez-Price, Josuel Delgado-Enciso, Ivan Delgado-Enciso
Clinical Epidemiology Research Unit, Mexican Social Security Institute, Av. Lapislazuli No. 250, El Haya, 28984, Villa de Álvarez, Colima, Mexico., Headquarters of Medical Services, Mexican Social Security Institute, Doroteo López 442, Col. Magisterial, Colima, Mexico., Clinical Laboratory, Mexican Social Security Institute. HGZ1, Av. Lapislazuli No. 250, El Haya, 28984, Villa de Álvarez, Colima, Mexico., Department of Research, Cancerology State Institute, Colima State Health Services, Liceo de Varones 401, La Esperanza, 28085, Colima, Colima, Mexico., Foundation for Ethics Education and Cancer Research of the IEC of Colima AC, Av. Liceo de Varones 401 Colonia la Esperanza, 28085, Colima, Mexico., Department of Research, Cancerology State Institute, Colima State Health Services, Liceo de Varones 401, La Esperanza, 28085, Colima, Colima, Mexico. .