New imaging technologies play a pivotal role in the current management of patients with prostate cancer. Robotic assisted radical prostatectomy (RARP) is a standard of care for localized disease and through the already imaging-based console subject of research towards combinations of imaging technologies and RARP as well as their impact on surgical outcomes. Therefore, we aimed to provide a comprehensive analysis of the currently available literature for new imaging technologies for RARP. On 24 January 2023, we performed a systematic review of the current literature on Pubmed, Scopus and Web of Science according to the PRISMA guidelines and Oxford levels of evidence. A total of 46 studies were identified of which 19 studies focus on imaging of the primary tumor, 12 studies on the intraoperative tumor detection of lymph nodes and 15 studies on the training of surgeons. While the feasibility of combined approaches using new imaging technologies including MRI, PSMA-PET CT or intraoperatively applied radioactive and fluorescent dyes has been demonstrated, the prospective confirmation of improvements in surgical outcomes is currently ongoing.
Journal of clinical medicine. 2023 Aug 21*** epublish ***
Severin Rodler, Marc Anwar Kidess, Thilo Westhofen, Karl-Friedrich Kowalewski, Ines Rivero Belenchon, Mark Taratkin, Stefano Puliatti, Juan Gómez Rivas, Alessandro Veccia, Pietro Piazza, Enrico Checcucci, Christian Georg Stief, Giovanni Enrico Cacciamani
Department of Urology, University Hospital of Munich, 81377 Munich, Germany., Department of Urology, Klinikum Mannheim, 68167 Mannheim, Germany., Urology and Nephrology Department, Virgen del Rocío University Hospital, Manuel Siurot s/n, 41013 Seville, Spain., Institute for Urology and Reproductive Health, Sechenov University, 117418 Moscow, Russia., Department of Urology, University of Modena and Reggio Emilia, 42122 Modena, Italy., Department of Urology, Hospital Clinico San Carlos, 28040 Madrid, Spain., Urology Unit, Azienda Ospedaliera Universitaria Integrata Verona, 37126 Verona, Italy., Division of Urology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy., Department of Surgery, Candiolo Cancer Institute, FPO-IRCCS, Candiolo, 10060 Turin, Italy., USC Institute of Urology, University of Southern California, Los Angeles, CA 90007, USA.