Tumor Mutational Burden in Metastatic Castration-Resistant Prostate Cancer and Response to Checkpoint Inhibition.

This single-center cohort study assesses the association of tumor mutational burden status in patients with metastatic castration-resistant prostate cancer and response to immune checkpoint inhibitor therapy.

JAMA oncology. 2024 Feb 08 [Epub ahead of print]

Peter D Zang, Neal S Chawla, Regina Barragan-Carrillo, Alex Chehrazi-Raffle, Abhishek Tripathi, Sumanta K Pal, Tanya B Dorff

Department of Medical Oncology & Experimental Therapeutics, City of Hope Comprehensive Cancer Center, Duarte, California.