BERKELEY, CA (UroToday.com) - Prostatic intraepithelial neoplasia (PIN), as a precursor to some prostatic carcinomas, was first described in the 1960s by McNeal under the name of ‘intraductal dysplasia’ and was more precisely characterized in 1986 by McNeal and Bostwick.[1]
PIN consists of pre-existing prostatic ducts and acini lined by cytologically atypical cells and is subdivided into low grade and high grade PIN (LGPIN and HGPIN). In its original description, PIN was subcategorized into three grades, with grade 1 equating to LGPIN and grades 2 – 3 combined into HGPIN...View or save the full text Mini Review as a .pdf file
Rodolfo Montironi, Roberta Mazzucchelli, Antonio Lopez-Beltran,* Marina Scarpelli, and Liang Cheng†
Institute of Pathological Anatomy, School of Medicine, Polytechnic University of the Marche Region (Ancona), United Hospitals, Ancona, Italy, *Unit of Anatomic Pathology, Cordoba University Medical School, Cordoba, Spain, and †Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA
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