OBJECTIVES:To analyze biochemical recurrence criteria, attending to different PSA-cut-points referred in the literature, and to review prostate cancer natural history.
METHODS: Review of the literature through a Medline search.
CONCLUSIONS: A PSA of 0.4 ng/ml followed by a value higher than the first, are the values that better define metastatic progression, while a PSA of 0.2 ng/ml followed by a value higher than the first could be more appropriate to define patients about to receive salvage radiotherapy. Nevertheless we need new markers in order to improve prognostic and natural history knowledge.
Written by:
Planas J, Morote J. Are you the author?
Programa de Investigación Traslacional en Cáncer de Próstata, Servicio de Urología, Instituto de Investigación Biomédica, Hospital Universitario Vall d'Hebron, Universidad Autónoma de Barcelona, España.
Reference: Arch Esp Urol. 2012 Jan-Feb;65(1):4-11.
PubMed Abstract
PMID: 22318173
Article in Spanish.
