Multiparametric prostate MRI for follow-up monitoring after radiation therapy - Abstract

ISSUE: Radiation therapy is a therapeutic option with curative intent for patients with prostate cancer.

Monitoring of prostate-specific antigen (PSA) values is the current standard of care in the follow-up. Imaging is recommended only for symptomatic patients and/or for further therapeutic options.

STANDARD RADIOLOGICAL METHODS: For detection of local recurrence magnetic resonance imaging (MRI) of the prostate is acknowledged as the method of choice.

PERFORMANCE: Good results for primary diagnosis were found especially in combination with functional techniques, whereas in recurrent prostate cancer only few studies with heterogeneous study design are available for prostate MRI. Furthermore, changes in different MRI modalities due to radiation therapy have been insufficiently investigated to date.

PRACTICAL RECOMMENDATIONS: As the initial results were promising prostate MRI and available therapeutic options for detection of local recurrence should be considered in patients with increased PSA.

Written by: 
Weidner AM, Dinter DJ, Bohrer M, Sertdemir M, Hausmann D, Wenz F, Schoenberg SO. Are you the author? 
Institut für Klinische Radiologie und Nuklearmedizin, Universitätsmedizin Mannheim, Medizinische Fakultät Mannheim der Universität Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Deutschland.

Reference: Radiologe. 2012 Mar;52(3):235-42. 
doi: 10.1007/s00117-011-2196-9

PubMed Abstract 
PMID: 22349898

Article in German.