Clinically insignificant prostate cancer is characterized by limited biologic malignancy and, possibly, it is suitable for non-radical treatment.
We performed a retrospective analysis of 1028 patients who underwent radical prostatectomy (118 of them with clinically insignificant prostate cancer), in order to assess the predictors of cancer-related outcome. Only 19% of the patients undergoing radical prostatectomy for clinically insignificant prostate cancer had clinically insignificant cancer in the prostatectomy specimen, whereas in 19% of the cases we found a high-risk disease. The risk of overtreatment is present but currently counterbalanced by the risk of undertreatment.
Written by:
Cova G, Beniamin F, Lamon C, Maccatrozzo L. Are you the author?
Struttura Complessa di Urologia, Ospedale "Ca Foncello" Treviso - Italy.
Reference: Urologia. 2012 Jun 21:0. Epub ahead of print.
doi: 10.5301/RU.2012.9365
PubMed Abstract
PMID: 22729603
Article in Italian.
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