BACKGROUND: Earlier reviews yielded contradictory results for reducing the risk of prostate cancer by physical activity.
METHODS: 32 Cohort studies and 17 case control studies taking the ones up to 2001 and the ones up to 2010 together. Additionally, subgroups from studies analyzing aggressive carcinomas and those after the age of 65 were presented separately.
RESULTS: In the mean, no risk reduction was found in earlier and in studies from the last 8 years with mostly imprecisely measured activity. In 7 studies with subgroups on aggressive forms a positive dose response relationship was documented, being significant in 3 studies. The subgroup over 65 years with high amount of physical activity yielded a significant effect in 3 studies.
CONCLUSIONS: Physical activity in leisure and in work fails to be protective but substantial evidence exists for an effective prevention by intensive physical activity.
Written by:
Heitkamp HC, Jelas I. Are you the author?
Abteilung Sportmedizin, Medizinische Klinik, Universitätsklinikum Tübingen, Silcherstr. 5, 72076, Tübingen, Deutschland.
Reference: Wien Med Wochenschr. 2012 Oct 12. Epub ahead of print.
doi: 10.1007/s10354-012-0121-0
PubMed Abstract
PMID: 23065019
Article in German.
UroToday.com Prostate Cancer Section
