BACKGROUND: Clear cell carcinoma of the prostate is rare, with the majority of reports consisting of a single case study.
CASE: We report a case of prostate cancer with unusual cytoplasmic clearing and a nested-like pattern of growth observed in an 80-year-old patient with lower urinary tract obstruction. Emphasis is placed upon differential diagnosis and the distinction from other clear cell carcinomas arising in the urinary tract, both at a histological and immunohistochemical level.
CONCLUSION: Androgen receptor immunohistochemistry seems to be a useful tool to distinguish prostate origin from secondary clear cell tumors.
Written by:
Varinot J, Drouin S, Rouprêt M, Montironi R, Lopez-Beltran A, Compérat E. Are you the author?
Public Assistance Hospital of Paris, Department of Pathology, La Pitié-Salpetriere Hospital, University UPMC Paris VI, Paris, France.
Reference: Anal Quant Cytol Histol. 2012 Oct;34(5):289-92.
PubMed Abstract
PMID: 23301389
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