Bone metastases from prostate cancer: 18F-fluoride PET/CT in a patient with discordant bone scintigraphy and 11C-choline PET/CT - Abstract

Bone scintigraphy has been used extensively in prostate cancer patients to detect bone involvement.

¹¹C-choline PET/CT is indicated when a biochemical recurrence is suspected, as this procedure is able to detect local recurrence, lymph-node infiltration, and metastases.In cases where the results of these 2 procedures do not coincide, MRI is then usually performed. ¹⁸F-fluoride may become an alternative to MRI for bone imaging.In our patient series, all bone lesions with ¹¹C-choline uptake were metastases. ¹⁸F-fluoride did not increase specificity of ¹¹C-choline but increased sensitivity of bone scintigraphy. CT helped in the interpretation of osteoarthritis and trauma lesions.

Written by:
Garcia G Jr, Riera E, Valls E, Soler M, Bassa P, Moragas M, Lomeña F.   Are you the author?
Unidad PET/TC CETIR-ERESA, 08950 Esplugues de Llobregat, Barcelona, Spain.

Reference: Clin Nucl Med. 2013 Feb;38(2):120-4.
doi: 10.1097/RLU.0b013e31827a20d3

PubMed Abstract
PMID: 23334127