ORLANDO, FL, USA (UroToday.com) - Jesse K. McKenney discussed how pathologists can improve active surveillance management protocols.
First, improvement of individualized Gleason score 7 risk estimates (Gleason score 3+4=7 and 4+3=7). Secondly, better identification of the architectural patterns present in the tumor. The challenge, "If risk estimates are improved, will this impact how biopsy tumor volume is used treatment decision-making?" Dr. McKenney concluded by saying, "Further stratification of a modified Gleason score 7 is possible, however, further studies in large AS cohorts are needed to evaluate the subtle histological differences.".
Presented by Jesse K McKenney, MD, Cleveland Clinic (OH) at the 2013 Genitourinary Cancers Symposium - February 14 - 16, 2013 - Rosen Shingle Creek - Orlando, Florida USA
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Reported for UroToday by Karen Roberts, Medical Editor